Prevalence of Vulvovaginal Candidiasis Among Women with Diabetes mellitus in Ibadan, Oyo State, Nigeria

Authors

  • O. E. Adebiyi
  • A. Oluwadun
  • O. J. Daniel
  • R. S. Oritogun
  • A. A. Fasanmade

Keywords:

Candidiasis, Diabetes Mellitus, Prevalence, Vulvovaginitis, Women

Abstract

Background: Diabetes mellitus predisposes to both bacterial and fungal infections, includingCandida species. Hitherto, Candida albicans has been identified as the most common opportunistic pathogen amongpatients with diabetes mellitus. More recently, Non-Candida albicans Candida (NCAC) species are increasingly recognized as the cause of candida infections.

Objective: To determine the prevalence of vulvovaginal candidiasis (VVC) as well as the species of Candida frequently identified among women with diabetes mellitus in Ibadan, Nigeria.

Methods: A cross-sectional study of 213 women diagnosed with diabetes mellitus was carried out in 2010. Direct microscopy and fungal cultures of high vaginal swabs were done using Sabouraud--Dextrose Agar and ChromAgar.

Results: The prevalence of VVC among 213 women with diabetic mellitus was 18.8% (40/213). The predominant Candida species isolated were Candida glabrata (30.0%), C. albicans and C. tropicalis (17.5%) each and C. Gulliermondii (15.0%). Diabetic women had higher rates of moderate and heavy growth of Candida density. Twenty-nine (72.5%) patients with candidiasis were symptomatic and the most common symptom was vulval/vaginal itching 48.3% (14/29).

Conclusion: This study put the prevalence rate of VVC among women with diabetes mellitus in Ibadan at 18.8%. The most common Candida species isolated was C.glabrata and majority of the patients were symptomatic.

Author Biographies

O. E. Adebiyi

Department of Medical Microbiology, University College Hospital, Ibadan, Oyo State

A. Oluwadun

Department of Medical Microbiology, Olabisi Onabanjo University, Sagamu, Ogun State

O. J. Daniel

Department of Community Medicine and Primary Care, Olabisi Onabanjo University Teaching Hospital Sagamu, Ogun State

R. S. Oritogun

Department of Community Medicine and Primary Care, Olabisi Onabanjo University Teaching Hospital Sagamu, Ogun State

A. A. Fasanmade

Department of Medicine, University College Hospital Ibadan, Oyo StatePrevalence of Vulvovaginal Candidiasis among women with Diabetes mellitus in Ibadan, Oyo State, Nigeria

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2016-03-24

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