Predictors of COVID-19 Vaccine Acceptance Among Nigerian Medical Doctors
DOI:
https://doi.org/10.30442/ahr.0801-01-152Keywords:
COVID-19, Nigeria, Pandemic, Physicians, SARS-COV2, Vaccine acceptance, Vaccine safetyAbstract
Background: Since its discovery in late 2019, COVID-19 has claimed approximately three million lives worldwide, causing a significant economic burden and strain on health care delivery and services. Therefore, the COVID-19 vaccine may offer the potential to promote global recovery.
Objective: To determine the acceptability of the COVID-19 vaccine among Nigerian doctors and the factors influencing the acceptance.
Methods: Using a cross-sectional design, an anonymous online survey was administered to medical doctors across the six geopolitical zones in Nigeria between 13 January and 31 January 2021, using the health belief model (HBM).
Results: Out of 830 respondents, 38.8% were willing to take the COVID-19 vaccine, 36.0% were unsure, while the remaining 26.5% refused to take the vaccine. Following adjustments, males were more likely to take the vaccine (OR = 3.357; 95% CI 2.009-5.610; p = 0.0001), whereas increasing age, higher perceived viral virulence and perceived viral infectivity were observed to be significantly associated with less likelihood of accepting the vaccine. Respondents who believed in the efficacy of ivermectin were much less likely to receive the vaccine (OR = 0.217; 95% CI 0.108-0.436; p = 0.001). Concerns on vaccination safety were the main barriers to vaccine acceptability. Hypothetically addressing these concerns increased vaccine acceptance rates by approximately a third (34.6%) (p < 0.001).
Conclusion: The proposed nationwide distribution of the COVID-19 vaccine may be met with poor vaccine acceptability among Nigerian medical practitioners. Measures specifically addressing vaccine safety concerns should be provided to allay fears and enhance the acceptability of the vaccine.
References
Doctors’ recommendations boost COVID-19 vaccine acceptance [Internet]. [cited 2021 Jul 6];Available from: https://www.umassmed.edu/news/news-archives/2021/06/doctors-recommendations-boost-covid-19-vaccine-acceptance/
Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. Int J Antimicrob Agents 2020; 55. https://doi.org/10.1016/j.ijantimicag.2020.105924
Du Toit A. Outbreak of a novel coronavirus. Nat Rev Microbiol 2020; 18. https://doi.org/10.1038/s41579-020-0332-0
NCDC Coronavirus COVID-19 Microsite [Internet]. [cited 2020 Jun 16]; Available from: https://covid19.ncdc.gov.ng/
WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus Disease (COVID-19) Dashboard [Internet]. [cited 2021 Mar 8]; Available from: https://covid19.who.int/
Responding to the Second Wave of COVID-19 in Africa – Africa CDC [Internet]. [cited 2021 March 8th];Available from: https://africacdc.org/download/responding-to-the-second-wave-of-covid-19-in-africa/
Impact of COVID-19 on people's livelihoods, their health and our food systems [Internet]. [cited 2021 Mar 8]; Available from: https://www.who.int/news/item/13-10-2020-impact-of-covid-19-on-people’s-livelihoods-their-health-and-our-food-systems
The Global Economic Outlook During the COVID-19 Pandemic: A Changed World [Internet]. [cited 2021 March 8th];Available from: https://www.worldbank.org/en/news/feature/2020/06/08/the-global-economic-outlook-during-the-covid-19-pandemic-a-changed-world
Advice for the public [Internet]. [cited 2021 Mar 8];Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public
Atalan A. Is the lockdown important to prevent the COVID-9 pandemic? Effects on psychology, environment and economy-perspective. Ann Med Surg 2020; 56: 38–42. https://doi.org/10.1016/j.amsu.2020.06.010
Wibawa T. COVID‐19 vaccine research and development: ethical issues. Trop Med Int Health 2021; 26: 14–9. https://doi.org/10.1111/tmi.13503
Covid-19 Vaccine Tracker Updates: The Latest - The New York Times [Internet]. [cited 2021 March 8th];Available from: https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html
Sallam M. COVID-19 vaccine hesitancy worldwide: a systematic review of vaccine acceptance rates. Vaccines (Basel) 2021; 9: 160. https://doi.org/10.3390/vaccine9020160
COVID-19 Vaccines Make Some Health Care Workers Wary : Shots - Health News : NPR [Internet]. [cited 2021 Sep 9]; Available from: https://www.npr.org/sections/health-shots/2020/12/01/940158684/some-health-care-workers-are-wary-of-getting-covid-19-vaccines
Nigeria | History, Population, Flag, Map, Languages, Capital, & Facts | Britannica [Internet]. [cited 2021 Sep 9];Available from: https://www.britannica.com/place/Nigeria
The DHS Program - Nigeria: DHS, 2013 - Final Report (English) [Internet]. [cited 2021 Sep 9];Available from: https://dhsprogram.com/publications/publication-fr293-dhs-final-reports.cfm
Coe AB, Gatewood SBS, Moczygemba LR, Goode J-V "Kelly" R. The use of the health belief model to assess predictors of intent to receive the novel (2009) H1N1 influenza vaccine. Inov Pharm 2012; 3. https://doi.org/10.24926/iip.v3i2.257
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. J. Int. Bioethique 2004;15:124–9.
van Oosterhout C, Hall N, Ly H, Tyler KM. COVID-19 evolution during the pandemic–Implications of new SARS-CoV-2 variants on disease control and public health policies. Virulence 2021; 12: 507–508. https://doi.org/10.1080/21505594.2021.1877066
Chou WYS, Budenz A. Considering Emotion in COVID-19 Vaccine Communication: Addressing Vaccine Hesitancy and Fostering Vaccine Confidence. Health Commun 2020; 35: 1718–1722. https://doi.org/10.1080/10410236.2020.1838096
Malik AA, McFadden SAM, Elharake J, Omer SB. Determinants of COVID-19 vaccine acceptance in the US. EClinicalMedicine 2020; 26. https://doi.org/10.1016/j.eclinm.2020.100495
Dror AA, Eisenbach N, Taiber S, Morozov NG, Mizrachi M, Zigron A, et al. Vaccine hesitancy: the next challenge in the fight against COVID-19. Eur J Epidemiol 2020; 35: 775–779. https://doi.org/10.1007/s10654-020-00671-y
Galbadage T, Peterson BM, Awada J, Buck AS, Ramirez DA, Wilson J, et al. Systematic review and meta-analysis of sex-specific COVID-19 clinical outcomes. medRxiv 2020; 2020.05.11.20098673. https://doi.org/10.1101/2020.05.11.20098673
Nri-Ezedi CA, Nnamani CP, Ezeh NI, Okechukwu C, Fasesan O, Ulasi TO. Psychological Distress among Residents in Nigeria during the COVID-19 Pandemic. Int Neuropsychiatr Dis J 2020; 14: 8–21. https://doi.org/10.9734/indj/2020/v14i330129
Torales J, O’Higgins M, Castaldelli-Maia JM, Ventriglio A. The outbreak of COVID-19 coronavirus and its impact on global mental health. Int J Soc Psychiatry 2020; 66: 317–320. https://doi.org/10.1177/0020764020915212
Restubog SLD, Ocampo ACG, Wang L. Taking control amidst the chaos: Emotion regulation during the COVID-19 pandemic. J Vocat Behav.2020; 119: 103440. https://doi.org/10.1016/j.jvb.2020.103440
Kumar BS, Jeyaraman M, Jain R, Anudeep TC. A Wonder Drug in the Arsenal against COVID - 19: Medication Evidence from Ivermectin. J Adv Med Med Res 2020; 32: 30-37. https://doi.org/10.9734/jammr/2020/v32i1030512
Chaccour C, Hammann F, Ramón-García S, Rabinovich NR. Ivermectin and COVID-19: Keeping rigor in times of urgency. Am J Trop Med Hyg 2020; 102: 1156–1157. https://doi.org/10.4269/ajtmh.20-0271
Rajter JC, Sherman MS, Fatteh N, Vogel F, Sacks J, Rajter J-J. ICON (Ivermectin in COvid Nineteen) Study: Use of Ivermectin Is Associated with Lower Mortality in Hospitalised Patients with Coronavirus Disease 2019. Chest 2021; 159: 85-92. https://doi.org/10.1016/j.chest.2020.10.009
Sear RF, Velasquez N, Leahy R, Restrepo NJ, Oud S El, Gabriel N, et al. Quantifying COVID-19 Content in the Online Health Opinion War Using Machine Learning. IEEE Access 2020; 8: 91886–93. https://doi.org/10.1109/ACCESS.2020.299
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