Autoamputation of the Breast in Invasive Ductal Carcinoma: A Case Report


  • MA Olusola-Bello
  • AA Olatunji
  • BA Ayoade
  • AO Adekoya
  • SB Ogunlade



Autoamputation is the spontaneous detachment from the body and elimination of an appendage or abnormal growth. Autoamputation of an organ due to malignancy has been reported in various organs, although its aetiopathogenesis has not been fully explained. Autoamputation of the breast is associated with late presentation and slow desmoplastic reaction in breast cancer. The patient was a 43- year- old Nigerian woman who presented with a one-year history of left breast mass diagnosed as triple negative invasive ductal carcinoma. She defaulted from hospital care but represented after autoamputation of the left breast. The case is reported to showcase the variations in the clinical course of breast cancers.


The Free Dictionary [Internet]. "autoamputation". Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, 7th Edition, Saunders, An imprint of Elsevier, Inc, 2003 [cited 26 February 2022]. Available from:

Lee K, Song M, Jung In: Lee Y, Park E. Amputation of an ovarian mature cystic teratoma: a case report and a review of the literature. World J Surg Oncol 2016; 14: 217.

Patel AK, Chaturvedi P, Panday RK, Sanyal B. Autoamputation of the tongue. Postgrad Med J 2001; 77: 335.

Agarwal P, Sharma D. Autodestruction of penis due to carcinoma of penis. J Eur Acad Dermatol Venereol 2005; 19: 220-222.

Mintz U, Keinan Z. Mammary "autoamputation" in inoperable carcinoma of the female breast. Harefuah 1975 1; 88: 531-532 [Article in Hebrew]

Van der Bijl P. Auto-amputation of a breast due to ductal carcinoma. S Afr Med J 2008; 98: 262–263.

Agarwal P, Sharma D. Autoamputation of breast following breast carcinoma. Internet J Surg 2009; 18: 262-264.

Firat D, Ozturk G, Demirbas E, Idiz O, Isik A, Eken H. Auto-Amputation of the Breast; a Rare Case Caused by Invasive Ductal Carcinoma. The Breast J 2017; 23: 102–103.

Elenwo SN, Dimoko AA, Ijah RF. Case Series: Auto-Amputation of the Breast in Patients with Advanced Breast Cancer. The Niger Health J 2020; 20: 72-77.

Ergül N, Kadıoğlu HÜ, Yıldız Ş, Yücel SB, Aydın M. Autoamputation of breast caused by invasive ductal carcinoma. Rev Esp Med Nucl Imagen Mol 2013; 32: 199-200.

Yang WT, Dryden MJ, Gwyn K, Whitman GJ, Theriault R. Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy. Radiology 2006; 239: 52-60.

Petrek JA, Dukoff R, Rogatko A. Prognosis of pregnancy-associated breast cancer. Cancer 1990; 67: 869e72

Martınez MT, Bermejo B, Hernando C, Gambardella V, Cejalvo JM, Lluch A. Breast Cancer in Pregnant Patients: A Review of the Literature. Eur J Obstet Gynecol Reprod Biol 2018; 230: 222-227.

Azim HA, Jr., Del Mastro L, Scarfone G, Peccatori FA. Treatment of breast cancer during pregnancy: regimen selection, pregnancy monitoring and more. Breast 2011; 20: 1-6.

Navrozoglou I, Vrekoussis T, Kontostolis E, Dousias V, Zervoudis S, Stathopoulos EN, et al. Breast cancer during pregnancy: a mini-review. Eur J Surg Oncol 2008; 34: 837e43.






Case Report

Most read articles by the same author(s)