Challenges of Thyroidectomy Anaesthesia for a Huge Retrosternal Goitre in a Jehovah’s Witness: A Case Report

Authors

  • O Ikokoh
  • AK Ojo
  • AO Adisa
  • AI Oria
  • JO Ajefolakemi

DOI:

https://doi.org/10.30442/ahr.1002-11-239

Abstract

In potential haemorrhagic surgical procedures, refusal of allogenic blood infusion poses a challenge to anaesthetists. This report is about a 65-year-old male, of the Jehovah’s Witness (JW) religious sect, known hypertensive, who presented with an anterior neck mass with retrosternal extension of three years. Laboratory investigations were normal, and the haemoglobin concentration was 13gm/dl. He consented to acute normovolaemic haemodilution (ANH). Therefore, two units of blood were drawn and replaced with isoplasma. The patient had a general anaesthesia relaxant technique. Intravenous tranexamic acid, morphine, and paracetamol were administered. A right-lobal thyroidectomy and sternotomy were performed. After securing haemostasis, the two blood units were infused, and the estimated blood loss was 1.5 litres. The surgery lasted for five and a half hours. After surgery, the patient was reversed of the neuromuscular blockade, extubated, transferred to the intensive care unit (ICU), and monitored for 24 hours. He had supplemental oxygenation, analgesia, and other supportive care. He was discharged on postoperative day seven and had attended the outpatient clinic for two months.

References

Klein AA, Bailey CR, Charlton A, Lawson C, Nimmo AF, Payne S, et al. Association of Anaesthetists: anaesthesia and peri-operative care for Jehovah's Witnesses and patients who refuse blood. Anaesthesia. 2019;74:74-482. https://doi.org/10.1111/anae.14441.

Klein AA, Arnold P, Bingham RM, Brohi K, Clark R, Collis R, et al. AAGBI Guidelines: The use of blood components and their alternatives 2016. Anaesthesia. 2016 ;71:829-842. https://doi.org/10.1111/anae.13489.

Muramoto O. Recent developments in medical care of Jehovah's Witnesses. West J Med. 1999;170:297–301.

Squire Y, Laxton C. Blood Conservation Techniques. Anaesthesia Tutorial of the Week 390. 2018;01:01- 07.

Murphy MF, Palmer A. Patient blood management as the standard of care. Haematology Am Soc Hematol Educ Program 2019:6:583-589. https://doi.org/10.1182/hematology.2019000063.

Muñoz M, Gómez-Ramírez S, Kozek-Langeneker S. Pre-operative haematological assessment in patients scheduled for major surgery. Anaesthesia. 2016;71 (1):19-28. doi: 10.1111/anae.13304.

Li Y, Zhang Y, Fang X. Acute normovolemic hemodilution in combination with tranexamic acid is an effective strategy for blood management in lumbar spinal fusion surgery. J Orthop Surg Res 2022;17:71. https://doi.org/10.1186/s13018-022-02950-8.

Klein AA, Bailey CR, Charlton AJ, Evans E, Guckian-Fisher M, McCrossan R, et al. Association of Anaesthetists Guidelines: Cell salvage for peri-operative blood conservation 2018. Anaesthesia. 2018;73:1141-1150. https://doi.org/10.1111/anae.14331.

Ikram M, Mahboob S. Anesthetic challenges in a large multinodular thyroidectomy at a peripheral hospital. Anaesth Pain Intensive Care 2019;23:311-313. https://doi.org/10.35975/apic.v23i3.1141

Jehovah’s Witnesses. How Many of Jehovah's Witnesses Are There Worldwide? [Accessed 18 October 2023]. Available online: https://www.jw.org/en/jehovahs-witnesses/faq/how-many-jw/

Hartrumpf M, Kuehnel RU, Ostovar R, Schroeter F, Albes JM. Everyday Cardiac Surgery in Jehovah's Witnesses of Typically Advanced Age: Clinical Outcome and Matched Comparison. J Clin Med. 2023;12:01-13. https://doi.org/10.3390/jcm12155110.

Lin ES, Kaye AD, Baluch AR. Preanesthetic Assessment of the Jehovah's Witness Patient. Ochsner J 2012;12:61-69.

Wojtczak B, Aporowicz M, Kaliszewski K, Bolanowski M. Consequences of bleeding after thyroid surgery - analysis of 7805 operations performed in a single centre. Arch Med Sci 2018;14:329-335. https://doi.org/10.5114/aoms.2016.63004.

Chen E, Cai Y, Li Q, Cheng P, Ni C, Jin L, et al. Risk factors target in patients with post-thyroidectomy bleeding. Int J Clin Exp Med 2014;7:1837-1844.

Grant MC, Resar LM, Frank SM. The Efficacy and Utility of Acute Normovolemic Hemodilution. Anesth Analg 2015;121:1412-1414. https://doi.org/10.1213/ANE.0000000000000935.

Wulff I, Duah HO, Yeboah AO, Tutu HO, Yankey KP. The efficacy and safety of intraoperative acute normovolaemic haemodilution in complex spine surgery in a private surgical facility in Ghana. Ghana Med J 2021;55:2-8. http://dx.doi.org/10.4314/gmj.v55i1.

Droz NM, Lin J, Beach J, Vo C, Morrow K, Lyden SP, et al. Decreased transfusion requirements with the use of acute normovolemic hemodilution in open aortic aneurysm repair. J Vasc Surg 2021;74:1885-1893. https://doi.org/10.1016/j.jvs.2021.05.030.

Acute Normovolemic Hemodilution in Total Knee Arthroplasty: A Prospective Study. Int Surg 2021;105:54–60. https://doi.org/10.9738/INTSURG-D-15-00149.1

Zhou X, Zhang C, Wang Y, Yu L, Yan M. Pre-operative Acute Normovolemic Hemodilution for Minimising Allogeneic Blood Transfusion: A Meta-Analysis. Anesth Analg2015;121:1443-1455. https://doi.org/10.1213/ANE.0000000000001010.

Waqar U, Tariq J, Chaudhry AA, Iftikhar H, Zafar H, Abbas SA. A Comprehensive Assessment of Blood Transfusions in Elective Thyroidectomy Based on 180,483 Patients. Laryngoscope 2022;132:2078-2084. https://doi.org/10.1002/lary.30098.

Youssef IA, Already MM, Attia JZ, Mahmoud MR. Acute Normovolemic Hemodilution. Minia J Med Res. 2021;32:69-70. https://doi:10.21608/mjmr.2022.220722.

Downloads

Published

2024-06-30

Issue

Section

Case Report