Endometrial Microcalcification in a 31-Year-Old Woman: A Case Report
DOI:
https://doi.org/10.30442/ahr.1003-09-249Keywords:
Amenorrhea, Endometrial calcification, Infertility, Placenta, Missed abortionAbstract
Endometrial microcalcifications are an uncommon event, though they may be a cause of amenorrhoea and infertility. It is often detected incidentally as echogenic lesions on ultrasonography and in endometrial samples sent for histopathological examination. A 31-year-old Para 0+3 presented with amenorrhoea and a “curettage sample” obtained from an evacuation performed for a missed abortion at ten weeks gestation. She brought the tissue obtained during the endometrial curettage, which was performed at a private hospital for histopathological examination and follow-up at the Gynaecology Clinic. A provisional diagnosis of atrophic endometrium was made following a pelvic ultrasound scan, while histopathological examination revealed placenta tissue with microcalcifications. The patient was subsequently placed on combined oral contraceptives for three cycles, having ruled out possible contraindications. She had regular per vaginam bleeding for three consecutive cycles. She resumed spontaneous menses and eventually achieved pregnancy. Although endometrial microcalcification is rare, it is a potential cause of secondary amenorrhea and infertility in women of reproductive age group.
References
Truskinovsky AM, Gerscovich EO, Duffield CR, Vogt PJ. Endometrial microcalcification detected by ultrasonography: clinical associations, histopathology, and potential etiology. Int J Gynecol Pathol 2008; 27: 61-67. https://doi.org/10.1097/pgp0b013e31812e95cb
AbdullGaffar B, AlMulla A. Endometrial Calcifications. Int J Surg Pathol 2020;28:590-599. https://doi.org/10.1177/1066896920909425
Ghashyam D, Mohd I, Arti K. Calcific endometritis as a cause of infertility: Ultrasonography as the main diagnostic modality. The Egypt J Radiol Nuclear Med 2016;47:1133-1136. https://doi.org/10.1016/j.ejrnm.2016.06.007
Ogbonmwan SE, Cher G. Endometrial ossification in postmenopausal women. J Obstet Gynaecol 2011;31:774-776. https://doi.org/10.3109/01443615.2011.599447
Tulandi T. Images in reproductive medicine. Endometrial cavity after microwave endometrial ablation. Fertil Steril 2000;73:598.
Pereira MC, Vaz MM, Miranda SP, Araújo SR, Menezes DB, das Chagas Medeiros F. Uterine cavity calcification: a report of 7 cases and a systematic literature review. J Minim Invasive Gynecol 2014;21:346-352. https://doi.org/10.1016/j.jmig.2013.11.001
Todani AK, Todani K. Isolated endometrial calcification presenting as primary amenorrhoea. J Obstet Gynaecol India 2015;65:60-64. https://doi.org/10.1007/s13224-014-0563-y
Zreik TG, Rutherford TJ. Psammoma bodies in cervicovaginal smears. Obstet Gynecol 2001;97:693-695. https://doi.org/10.1016/s0029-7844(01)01124-3
Alorini M, Aziz M, Gromez A, Piton N, Sabourin JC. Métaplasie osseuse de l’endomètre : à propos d’un cas [Endometrial osseous metaplasia: A case report]. Ann Pathol 2017;37:488-490. https://doi.org/10.1016/j.annpat.2017.10.011
Herbold DR, Magrane DM. Calcifications of the benign endometrium. Arch Pathol Lab Med 1986;110:666-669.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Annals of Health Research (The Journal of the Medical and Dental Consultants Association of Nigeria, OOUTH, Sagamu, Nigeria)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The articles and other materials published in the Annals of Health Research are protected by the Nigerian Copyright laws. The journal owns the copyright over every article, scientific and intellectual materials published in it. However, the journal grants all authors, users and researchers access to the materials published in the journal with the permission to copy, use and distribute the materials contained therein only for academic, scientific and non-commercial purposes.